{"id":162,"date":"2025-03-28T16:31:35","date_gmt":"2025-03-28T07:31:35","guid":{"rendered":"https:\/\/ookayama-kodomo.com\/blog\/?p=162"},"modified":"2026-01-22T11:19:16","modified_gmt":"2026-01-22T02:19:16","slug":"%e3%82%a2%e3%83%88%e3%83%94%e3%83%bc%e6%80%a7%e7%9a%ae%e8%86%9a%e7%82%8e%e6%b2%bb%e7%99%82%e8%96%ac%e3%83%bb%e3%83%a2%e3%82%a4%e3%82%bc%e3%83%ab%e3%83%88%e8%bb%9f%e8%86%8f%e3%81%a8%e3%81%af","status":"publish","type":"post","link":"https:\/\/ookayama-kodomo.com\/blog\/?p=162","title":{"rendered":"\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u6cbb\u7642\u85ac\u30fb\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f\u3068\u306f"},"content":{"rendered":"\n<h1 class=\"wp-block-heading\">\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f\u3068\u306f<\/h1>\n\n\n\n<p>\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f\uff08\u4e00\u822c\u540d\uff1a\u30b8\u30d5\u30a1\u30df\u30e9\u30b9\u30c8\uff09\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u5916\u7528\u85ac\u3068\u306f\u7570\u306a\u308b\u4f5c\u7528\u6a5f\u5e8f\u3092\u6301\u3061\u3001\u526f\u4f5c\u7528\u304c\u5c11\u306a\u304f\u3001\u5b89\u5168\u6027\u304c\u9ad8\u3044\u306e\u304c\u7279\u5fb4\u3067\u3059\u3002\u30b9\u30c6\u30ed\u30a4\u30c9\u3067\u75c7\u72b6\u3092\u3057\u3063\u304b\u308a\u3068\u6291\u3048\u305f\u5f8c\u306b\u7f6e\u304d\u63db\u3048\u3066\u4f7f\u3046\u3053\u3068\u3067\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u4f7f\u7528\u3092\u6e1b\u3089\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u307e\u305f\u3001\u8efd\u75c7\u306e\u60a3\u8005\u69d8\u3067\u3042\u308c\u3070\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f\u306e\u307f\u3067\u6cbb\u7642\u3059\u308b\u3053\u3068\u3082\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<h1 class=\"wp-block-heading\">\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f\u306e\u7279\u5fb4<\/h1>\n\n\n\n<p>\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f\u306f\u56fd\u5185\u3067\u521d\u3081\u3066\u306ePDE4\uff08\u30db\u30b9\u30db\u30b8\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc4\uff09\u963b\u5bb3\u5264\u3067\u3059\u3002<br>PDE4\u306f\u708e\u75c7\u3092\u8d77\u3053\u3059\u514d\u75ab\u7d30\u80de\u306e\u591a\u304f\u306b\u5b58\u5728\u3057\u3001\u7d30\u80de\u5185\u30bb\u30ab\u30f3\u30c9\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fc\u3067\u3042\u308b\u30b5\u30a4\u30af\u30ea\u30c3\u30afAMP\uff08cAMP\uff09\u3092\u5206\u89e3\u3059\u308b\u50cd\u304d\u304c\u3042\u308a\u307e\u3059\u3002cAMP\u306f\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u7523\u751f\u6291\u5236\u306b\u95a2\u308f\u3063\u3066\u304a\u308a\u3001cAMP\u304cPDE4\u306b\u3088\u3063\u3066\u5206\u89e3\u3055\u308c\u308b\u3068\u3001\u708e\u75c7\u53cd\u5fdc\u304c\u751f\u3058\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<br>\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f\u306f\u3001PDE4\u306e\u6d3b\u6027\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u3067\u708e\u75c7\u7d30\u80de\u5185\u306ecAMP\u6fc3\u5ea6\u3092\u9ad8\u3081\u3001\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u3092\u542b\u3080\u7269\u8cea\u306e\u7523\u751f\u3092\u6291\u5236\u3057\u3001\u76ae\u819a\u306e\u708e\u75c7\u3092\u7de9\u548c\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1021\" height=\"1024\" src=\"https:\/\/ookayama-kodomo.com\/blog\/wp-content\/uploads\/2025\/03\/image2.png\" alt=\"\" class=\"wp-image-164\" srcset=\"https:\/\/ookayama-kodomo.com\/blog\/wp-content\/uploads\/2025\/03\/image2.png 1021w, https:\/\/ookayama-kodomo.com\/blog\/wp-content\/uploads\/2025\/03\/image2-300x300.png 300w, https:\/\/ookayama-kodomo.com\/blog\/wp-content\/uploads\/2025\/03\/image2-150x150.png 150w, https:\/\/ookayama-kodomo.com\/blog\/wp-content\/uploads\/2025\/03\/image2-768x770.png 768w\" sizes=\"auto, (max-width: 1021px) 100vw, 1021px\" \/><\/figure>\n<\/div>\n\n\n<h1 class=\"wp-block-heading\">\u6cbb\u7642\u306e\u5bfe\u8c61\u3068\u306a\u308b\u65b9<\/h1>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u751f\u5f8c3\u304b\u6708\u4ee5\u964d\u306e\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u65b9<\/li>\n<\/ul>\n\n\n\n<h1 class=\"wp-block-heading\">\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f\u306e\u4f7f\u7528\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u306a\u65b9<\/h1>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u598a\u5a20\u4e2d\u307e\u305f\u306f\u598a\u5a20\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u65b9<\/li>\n\n\n\n<li>\u6388\u4e73\u4e2d\u306e\u65b9<\/li>\n<\/ul>\n\n\n\n<h1 class=\"wp-block-heading\">\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f\u306e\u526f\u4f5c\u7528<\/h1>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u81e8\u5e8a\u8a66\u9a13\u306b\u304a\u3044\u3066\u91cd\u7be4\u306a\u526f\u4f5c\u7528<\/li>\n\n\n\n<li>\u7a00\u306b\u5857\u3063\u305f\u90e8\u5206\u304c\u304b\u3076\u308c\u3066\u3057\u307e\u3046\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u306e\u969b\u306f\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044<\/li>\n<\/ul>\n\n\n\n<h1 class=\"wp-block-heading\">\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f\u306e\u4f7f\u7528\u65b9\u6cd5<\/h1>\n\n\n\n<p>\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f\u306f\u6fc3\u5ea6\u304c\uff12\u7a2e\u985e\uff080.3%\u30fb1.0%\uff09\u3042\u308a\u3001\u751f\u5f8c3\u30f6\u6708\u4ee5\u4e0a\uff5e14\u6b73\u4ee5\u4e0b\u306e\u5c0f\u5150\u306e\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u65b9\u306f\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f0.3%\u304b1.0%\u306e\u3044\u305a\u308c\u304b\u3092\u304a\u4f7f\u3044\u3044\u305f\u3060\u3051\u307e\u3059\u3002<br>\u6210\u4eba\u306e\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u65b9\u306f\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f1.0\uff05\u88fd\u5264\u3068\u3055\u308c\u3066\u304a\u308a0.3%\u88fd\u5264\u306f\u304a\u4f7f\u3044\u3044\u305f\u3060\u3051\u307e\u305b\u3093\u3002\u4f7f\u7528\u65b9\u6cd5\u306f\u5c0f\u5150\u30fb\u6210\u4eba\u3068\u30821\u65e52\u56de\u9069\u91cf\u3092\u60a3\u90e8\u306b\u5857\u5e03\u3057\u3066\u4f7f\u7528\u3057\u307e\u3059\u30021\u56de\u306e\u5857\u5e03\u91cf\u306e\u5236\u9650\u306f\u7121\u304f\u3001\u76ae\u75b9\u306e\u9762\u7a4d\u306b\u5fdc\u3058\u3066\u3054\u4f7f\u7528\u3044\u305f\u3060\u304f\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"337\" height=\"339\" src=\"https:\/\/ookayama-kodomo.com\/blog\/wp-content\/uploads\/2025\/03\/image3.png\" alt=\"\" class=\"wp-image-165\" srcset=\"https:\/\/ookayama-kodomo.com\/blog\/wp-content\/uploads\/2025\/03\/image3.png 337w, https:\/\/ookayama-kodomo.com\/blog\/wp-content\/uploads\/2025\/03\/image3-298x300.png 298w, https:\/\/ookayama-kodomo.com\/blog\/wp-content\/uploads\/2025\/03\/image3-150x150.png 150w\" sizes=\"auto, (max-width: 337px) 100vw, 337px\" \/><\/figure>\n<\/div>\n\n\n<h1 class=\"wp-block-heading\">\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f\u306e\u8cbb\u7528\u306b\u3064\u3044\u3066<\/h1>\n\n\n\n<p>\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f1\uff05\u306f28g\u30c1\u30e5\u30fc\u30d6\u3067\u3042\u308c\u30703\u5272\u8ca0\u62c5\u306e\u60a3\u8005\u69d8\u3067\u306f1,263\u5186\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h1 class=\"wp-block-heading\">\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f\u306e\u8a71\u984c<\/h1>\n\n\n\n<p><a href=\"https:\/\/news.yahoo.co.jp\/expert\/articles\/29a9accf17afb717d97d15998e252c88d309fdef\" target=\"_blank\" rel=\"noreferrer noopener\">\u76ae\u819a\u75be\u60a3\u6cbb\u7642\u306e\u9769\u65b0\uff1aPDE4\u963b\u5bb3\u85ac\u306e\u53ef\u80fd\u6027\u3092\u63a2\u308b<\/a><\/p>\n\n\n\n<p>\u5927\u7530\u533a\u3001\u76ee\u9ed2\u533a\u3001\u6771\u6025\u76ee\u9ed2\u7dda\u6cbf\u3044\uff08\u7530\u5712\u8abf\u5e03\u3001\u5965\u6ca2\u3001\u5927\u5ca1\u5c71\u3001\u6d17\u8db3\u3001\u897f\u5c0f\u5c71\u3001\u6b66\u8535\u5c0f\u5c71\u306a\u3069\uff09\u3001\u6771\u6025\u5927\u4e95\u753a\u7dda\u6cbf\u3044\uff08\u81ea\u7531\u304c\u4e18\u3001\u7dd1\u304c\u4e18\u3001\u5927\u5ca1\u5c71\u3001\u65d7\u306e\u53f0\u306a\u3069\uff09\u3067\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u8a3a\u5bdf\u3092\u3054\u5e0c\u671b\u65b9\u306f\u305c\u3072\u4e00\u5ea6\u3001\u5927\u5ca1\u5c71\u3053\u3069\u3082\u30a2\u30ec\u30eb\u30ae\u30fc\u30af\u30ea\u30cb\u30c3\u30af\u3078\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f\u3068\u306f \u30e2\u30a4\u30bc\u30eb\u30c8\u8edf\u818f\uff08\u4e00\u822c\u540d\uff1a\u30b8\u30d5\u30a1\u30df\u30e9\u30b9\u30c8\uff09\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u5916\u7528\u85ac\u3068\u306f\u7570\u306a\u308b\u4f5c\u7528\u6a5f\u5e8f\u3092\u6301\u3061\u3001\u526f\u4f5c\u7528\u304c\u5c11\u306a\u304f\u3001\u5b89\u5168\u6027\u304c\u9ad8\u3044\u306e\u304c\u7279\u5fb4\u3067\u3059\u3002\u30b9\u30c6\u30ed\u30a4\u30c9\u3067\u75c7\u72b6\u3092\u3057\u3063\u304b\u308a\u3068\u6291\u3048\u305f\u5f8c\u306b\u7f6e\u304d\u63db\u3048\u3066\u4f7f\u3046\u3053\u3068\u3067\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u306e [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":163,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[22,16],"tags":[],"class_list":{"0":"post-162","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-22","8":"category-16"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/ookayama-kodomo.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/162","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ookayama-kodomo.com\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ookayama-kodomo.com\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ookayama-kodomo.com\/blog\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/ookayama-kodomo.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=162"}],"version-history":[{"count":4,"href":"https:\/\/ookayama-kodomo.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/162\/revisions"}],"predecessor-version":[{"id":277,"href":"https:\/\/ookayama-kodomo.com\/blog\/index.php?rest_route=\/wp\/v2\/posts\/162\/revisions\/277"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ookayama-kodomo.com\/blog\/index.php?rest_route=\/wp\/v2\/media\/163"}],"wp:attachment":[{"href":"https:\/\/ookayama-kodomo.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=162"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ookayama-kodomo.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=162"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ookayama-kodomo.com\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=162"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}